Top 5 Calming Pills That Really Work (No Prescription Needed)

June 2024

Do you suffer from stress or depression? Do you feel anxious? Do you have less energy to do things?

You probably have the feeling that you will never be the same again, but that is not true.

Over the past few years, you probably noticed how many calming tablets and other anti-stress products are sold in drugstores.

Do these supplements really work? Or is it just a placebo effect?

Since I am a nutritionist, I have thoroughly researched all the available anti-anxiety and calming products. Based on this, I created a top 5 list of products that actually help with stress, depression and anxiety.

Do calming tablets really work?

It’s important to know that there are two types of anti-anxiety products:

  • Calming medications
  • Natural calming products

Calming medications are addictive and can have negative effects on your mental and physical health. This medication is prescribed as a very last resort. I do not recommend the use of this medication and I will not go into detail in this article.

Natural calming products are made from natural plant extracts. For this reason, they are not addictive and have positive effects on your mental and physical health.

Now you are probably wondering if these natural calming products really work.

I have read over 60 scientific studies to find out if these products really have an effect.

Each study shows that these plant extracts can actually reduce your stress, a burnout and anxiety.

Top 5 Best calming products

3Nytol Herbal3/10
5Bach Rescue Remedy1/10

1. Restilen

These are the best anti-anxiety pills I have tested. With these pills you will not experience stress and anxiety anymore. You will get motivation to do things again.

The composition is patented, which makes Restilen better than the other products. Restilen contains the best and purest ingredients make you feel calm again: Serenzo™, KSM-66®, Saffr’Activ®, SOD B Extramel®, Aquamin™ Mg and 8 more active ingredients.

Multiple scientific studies have shown that the Restilen pills reduce your stress and anxiety [1] [2].

Since last year, I experienced a lot of stress and anxiety. I assume that I was suffering from a burnout. Every other day, I was suffering from palpitations and hyperventilation. It was very annoying and made it difficult to reach my goals.

I had ordered the Restilen pills online and chose 3 packages. They have a temporary promotion. If you buy 3 packages of Restilen, you get 3 for free. You will receive 6 packages, of which 3 are free. It is a good idea to get some extra packages with the promotion, you might need them in the future.

The packaging was very convenient, I couldn’t see or guess what was in the package after it was delivered the next day.

Warning: The Restilen pills may not be suitable for pregnant women and nursing mothers. Always have the ingredients in products checked by your doctor

Every day, I took 1 pill in the morning and 1 pill before going to bed. I noticed a difference 30 minutes after taking the pill. I felt very calm, normally I felt like my chest was tight. This feeling was gone, also I had stopped worrying. Finally, I could do the things I wanted to do again, I had my motivation back. I could finally fall asleep at night, without any bad thoughts.

Personally, I am a big fan of Restilen. It feels amazing to have a life without stress and anxiety.


  • Effectivity 10/10
  • Best natural calming pills
  • No prescription needed
  • Best pills against anxiety and depression
  • 100% natural and safe
  • Improves your mood
  • Reduces stress, a burnout and anxiety
  • Easier to fall asleep and a better sleep
  • Provides motivation and gives an energy boost
  • Effectivity scientifically proven

Check the prices of Restilen here

2. AdrenalStability

AdrenalStabilityThe number 2 calming product in our top 5 is AdrenalStability. These anti-stress pills are well known to calm you down and you will experience a better sleep.

  • Effectivity 7/10
  • Improves mood
  • Makes you feel calm
  • 100% Natural
  • Improve sleep

The main component in AdrenalStability is: Ashwagandha.

According to scientific research, Ashwagandha makes you feel calm.

Restilen is cheaper than AdrenalStability and works a lot better. Therefore, I recommend Restilen.

Check the prices of AdrenalStability here

3. Nytol Herbal

nytolNytol Herbal is a product against stress, fatigue and anxiety. The manufacturer of Nytol is Omega Pharma Ltd.

The ingredients in Nytol Herbal are: Hops, Valerian and PassionFlower.

Hops is the main ingredient in Nytol Herbal. Multiple studies have shown that Hops can help with depression [3].

I recommend this product if you are looking for an inexpensive product that will improve your mood.

  • Effectivity 3 /10
  • Improves the mood a little
  • A bit more rest

Check the prices of Nytol Herbal here

4. Kalms

kalmsKalms is one of the most popular calming tablets. The manufacturer claims that their product will make you feel calm and less stressed.

We have tried these tablets ourselves and it turns out that they do not work at all.

If you look at the ingredients of the tablets, you can see why they do not work.

The only active ingredient in Kalms is: Valerian.

There is not enough research done on Kalms yet. According to most scientists, the effect is not yet proven [5].

  • Effectivity 2 /10
  • Almost no effect
  • Underdosed

Check the prices of Kalms here

5. Bach Rescue Remedy

bach rescueThe most known calming product is Rescue Remedy. These are drops instead of pills. They are available at every drugstore, so many people buy them.

Most people don’t know that this anti-stress product is not effective. These drops do not contain any special ingredients. The only calming ingredient in Rescue Remedy is grape alcohol.

The other ingredients in Rescue Remedy are not scientifically proven to help with stress or anxiety.

  • Effectivity 1/10
  • According to science, it is nonsense
  • Contains alcohol
  • Available at every drugstore

Check the prices of Rescue Remedy here


There are many anti-anxiety pills available to make you feel calm and reduce your stress. Many products do not work and are a waste of money.

According to my own experience and the experience of others, Restilen works very well against stress, a burnout and anxiety.

Restilen contains more than 10 active ingredients that are highly dosed. Restilen is the only proven effective and natural product.


  1. I bought Kalms at Guardian, it didn’t work at all. After that, I placed an order for Restilen because a friend told me it works very well. I took 1 tablet in the morning and I felt very calm at work. No more stress and anxiety at all. I am super satisfied with Restilen, you pay a bit more the quality is amazing.

    • Hi Vyvyanh,

      Kalms does not work, it is only a placebo effect. Though that is what you get for that price.
      I am glad to hear that you are doing well.

    • Hi Vyvyanh, I just placed a Restilen order. How long did the delivery take?

  2. I have been using the Restilen pills for six months and they have changed my life. I used to get anxious very easily. I started using Restilen and I became calm again and found peace. I am no longer taking Restilen pills and feel better than ever.

  3. Hi Cindy,

    I am taking Restilen daily and it works really well. I fear habituation or addiction. Can you give me more information about this?

    Kind regards,


    • Hi Stephen,

      No habituation takes place when using Restilen.
      Restilen is not addictive.

  4. Hello Cindy, Can I use restillen with anti-depressants ?

    • Hi Sharon,

      Yes, that is possible. All ingredients in Restilen work well combined with anti-depressants.


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